Nuevos productos para el estudio del inflammasome

inflammasome

Como proveedor líder de productos para el estudio de la inmunidad innata, InvivoGen ofrece una amplia selección de líneas celulares para el estudio del inflammasome de alta calidad, así como una gran colección de inhibidores y anticuerpos.

NEW INFLAMMASOME CELL LINES:
Gasdermin-D KO THP-1 Cells
InvivoGen has developed THP1-KO-GSDMD cells, which were generated from the human monocytic THP-1 cell line THP1-Null2, through the stable knockout of the GSDMD gene.

Gasdermin-D KO RAW-ASC Cells
GSDMD Knockout & ASC expressing RAW 264.7 cells (murine macrophages)

Caspase-4 KO THP-1 Cells
CASP4 Knockout in THP-1 cells (human monocytes)

Caspase-11 KO RAW-ASC Cells
Caspase-11 Knockout & ASC expressing RAW 264.7 cells (murine macrophages)


NEW INHIBITORS:
Remdesivir
Remdesivir, also known as GS-5734, is a 1’-cyano-substituted adenosine nucleotide analog prodrug that shows broad-spectrum antiviral activity.

Human cGAS inhibitor (G140)
G140 is a small-molecule inhibitor of the double-stranded DNA (dsDNA) sensor, cGAS (cyclic GMP-AMP synthase; cGAMP synthase).
 
NEW CLINICALLY RELEVANT ANTIBODIES:
Anti-hIL6R (Tocilizumab) mAbs
Recombinant monoclonal human IgG1, IgG1NQ and IgA2 antibodies against IL-6R (Tocilizumab)
 

Comparte y disfruta